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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
3.03
Human Site:
S464
Identified Species:
5.13
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S464
P
T
P
Q
S
V
P
S
P
A
P
T
P
F
P
Chimpanzee
Pan troglodytes
XP_509441
819
90122
P434
P
V
T
Q
P
P
Q
P
R
L
T
F
V
H
P
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
T27
S
P
D
S
D
S
D
T
D
S
E
D
P
S
L
Dog
Lupus familis
XP_546925
857
93734
P469
G
P
G
P
A
P
P
P
F
P
I
D
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
D476
G
P
V
P
F
S
V
D
H
L
P
H
G
Y
L
Rat
Rattus norvegicus
Q6AXT8
471
49872
K108
K
V
K
V
E
V
K
K
F
V
K
I
G
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
A508
P
L
G
Y
P
S
P
A
A
P
Q
H
L
P
P
Frog
Xenopus laevis
NP_001084764
548
60887
V185
W
K
R
R
I
E
I
V
V
R
E
Y
H
K
W
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
V439
T
H
T
A
S
S
T
V
T
P
T
D
A
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
H443
P
F
A
V
P
K
Y
H
S
K
S
K
S
R
V
Honey Bee
Apis mellifera
XP_394429
1014
115124
R625
P
K
Y
Q
M
K
A
R
N
R
S
R
S
S
S
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
S526
Q
P
T
P
Q
P
Q
S
H
D
P
M
M
A
P
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
T926
A
D
T
R
S
K
T
T
F
K
L
Q
T
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
P696
P
P
P
P
P
P
P
P
P
M
Q
H
S
T
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
20
6.6
13.3
N.A.
6.6
13.3
N.A.
N.A.
20
0
6.6
N.A.
6.6
13.3
20
13.3
P-Site Similarity:
100
20
20
20
N.A.
13.3
13.3
N.A.
N.A.
26.6
6.6
6.6
N.A.
6.6
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
0
8
8
8
8
0
0
8
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
0
8
8
8
8
0
22
0
0
0
% D
% Glu:
0
0
0
0
8
8
0
0
0
0
15
0
0
0
0
% E
% Phe:
0
8
0
0
8
0
0
0
22
0
0
8
0
8
0
% F
% Gly:
15
0
15
0
0
0
0
0
0
0
0
0
15
0
0
% G
% His:
0
8
0
0
0
0
0
8
15
0
0
22
8
8
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
0
8
8
0
0
0
% I
% Lys:
8
15
8
0
0
22
8
8
0
15
8
8
0
15
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
15
8
0
15
8
15
% L
% Met:
0
0
0
0
8
0
0
0
0
8
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
43
36
15
29
29
29
29
22
15
22
22
0
15
8
50
% P
% Gln:
8
0
0
22
8
0
15
0
0
0
15
8
0
0
0
% Q
% Arg:
0
0
8
15
0
0
0
8
8
15
0
8
0
15
0
% R
% Ser:
8
0
0
8
22
29
0
15
8
8
15
0
22
15
8
% S
% Thr:
8
8
29
0
0
0
15
15
8
0
15
8
8
8
8
% T
% Val:
0
15
8
15
0
15
8
15
8
8
0
0
8
0
15
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
8
8
0
0
8
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _